Manchester United take on Southampton on Saturday 12 February at Old Trafford in Matchday 25 of the Premier League.
Saturday, January 22, at the St. Mary's Stadium will host a duel between Southampton and Manchester City in the 23rd round of the English Premier League.
On Saturday, October 2, Chelsea and Southampton will play at Stamford Bridge Stadium as part of the 7th round of the English Premier League.
On Sunday, August 22, at St Mary's Stadium, the match between Southampton and Manchester United will take place within the framework of the 2nd round of the English Premier League.
